C-Trap Optical Tweezers In the Tans Biophysics Group we study the dynamics of single proteins and cells using novel experimental approaches. At the molecular level, we use optical tweezers and single-molecule fluorescence to reveal how chaperones are able to fold amino-acid chains into functional proteins, and prevent protein-malfunction diseases. For this purpuse we use the commercially available Lumicks C-Trap or home-built optical trapping systems

Lightsheet Microscope At the cellular level, we use various types of time-lapse microscopy and image analysis to understand how single cells and multi-cellular systems are able to self-organise A Nikon Multiphoton Confocal Microscope and a Home-built Light Sheet Microscope